Journal of Human Reproductive Sciences

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 10  |  Issue : 2  |  Page : 86--90

To study the vitamin D levels in infertile females and correlation of Vitamin D deficiency with AMH levels in comparison to fertile females


Indu Lata1, Swasti Tiwari2, Amrit Gupta1, Subhash Yadav3, Shashi Yadav2 
1 Department of Maternal and Reproductive Health, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
2 Department of Molecular Biology and Biotechnology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
3 Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India

Correspondence Address:
Indu Lata
Department of Maternal and Reproductive Health, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh
India

Context: Human and animal data suggest that low vitamin D (25-hydroxyvitamin D) status is associated with impaired fertility, endometriosis, and polycystic ovary syndrome. Vitamin D regulates antimullerian hormone (AMH), FSH, mRNA, and expression of genes in reproductive tissues, implicating a role in female reproduction. Aims: To study the vitamin D levels in infertile females and to know the correlation of vitamin D deficiency (VDD) with serum AMH in infertile females compare to fertile females. Settings And Design: This prospective study was conducted in department of Maternal and Reproductive Health in between April 2014 and April 2016. Materials and Methods: After matching inclusion and exclusion criteria out of total 70 infertile females, 45 were found to have VDD. Of these 35 patients were identified as cases; in whom, the AMH levels were assessed. As control 35 fertile normal females were taken, in which vitamin D and AMH were taken. In both groups, correlation of VDD with AMH was studied. Statistical Analysis Used: To analyze the correlation between vitamin D and AMH linear regression test and for comparison of both the groups, two sample t tests were used. Results: The VDD was present in 64.28% of infertile females. In vitamin D deficient cases, the mean for vitamin D was 6.18 ± 2.09 and AMH was 1.94 ± 1.30. In vitamin D deficient controls, the mean for vitamin D was 4.85 ± 3.02 and AMH was 3.47 ± 2.59. On comparison, the vitamin D levels were lower in fertile than infertile females, which was significant (P = 0.04), and AMH levels were lower in cases than control group (P = 0.003). Conclusion: The VDD was present in 64.28% of infertile females. No significant correlation was found in between VDD and AMH levels in both the groups.


How to cite this article:
Lata I, Tiwari S, Gupta A, Yadav S, Yadav S. To study the vitamin D levels in infertile females and correlation of Vitamin D deficiency with AMH levels in comparison to fertile females.J Hum Reprod Sci 2017;10:86-90


How to cite this URL:
Lata I, Tiwari S, Gupta A, Yadav S, Yadav S. To study the vitamin D levels in infertile females and correlation of Vitamin D deficiency with AMH levels in comparison to fertile females. J Hum Reprod Sci [serial online] 2017 [cited 2023 Feb 4 ];10:86-90
Available from: https://www.jhrsonline.org/article.asp?issn=0974-1208;year=2017;volume=10;issue=2;spage=86;epage=90;aulast=Lata;type=0