Journal of Human Reproductive Sciences

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 7  |  Issue : 3  |  Page : 194--197

A comparative study between cleavage stage embryo transfer at day 3 and blastocyst stage transfer at day 5 in in-vitro fertilization/intra-cytoplasmic sperm injection on clinical pregnancy rates


Prabhleen Kaur, ML Swarankar, Manju Maheshwari, Veena Acharya 
 Department of Obstetrics and Gynecology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India

Correspondence Address:
Prabhleen Kaur
A 2/93 Janakpuri, New Delhi - 110 058
India

Objective: To evaluate the efficacy of blastocyst transfer in comparison with cleavage stage transfer. Study Design: A randomized, prospective study was conducted in Infertility clinic, Department of Obstetrics and Gynecology, Mahatma Gandhi Hospital, Jaipur on 300 patients aged 25-40 years undergoing in-vitro fertilization (IVF)/intra-cytoplasmic sperm injection (ICSI) cycle from May 2010-April 2011. When three or more Grade-I embryos were observed on day 2 of culture, patients were divided randomly into two study groups, cleavage stage transfer and blastocyst transfer group having 150 patients each. Primary outcomes evaluated were, Clinical pregnancy rate and Implantation rate. The results were analyzed using proportions, standard deviation and Chi-square test. Results: Both the groups were similar for age, indication and number of embryos transferred. Clinical pregnancies after blastocyst transfer were significantly higher 66 (44.0%) compared to cleavage stage embryo transfer 44 (29.33%) (P < 0.01).Implantation rate for blastocyst transfer group was also significantly higher (P < 0.001). Conclusion: Blastocyst transfer having higher implantation rate and clinical pregnancy rate lead to reduction in multiple pregnancies.


How to cite this article:
Kaur P, Swarankar M L, Maheshwari M, Acharya V. A comparative study between cleavage stage embryo transfer at day 3 and blastocyst stage transfer at day 5 in in-vitro fertilization/intra-cytoplasmic sperm injection on clinical pregnancy rates.J Hum Reprod Sci 2014;7:194-197


How to cite this URL:
Kaur P, Swarankar M L, Maheshwari M, Acharya V. A comparative study between cleavage stage embryo transfer at day 3 and blastocyst stage transfer at day 5 in in-vitro fertilization/intra-cytoplasmic sperm injection on clinical pregnancy rates. J Hum Reprod Sci [serial online] 2014 [cited 2020 Oct 20 ];7:194-197
Available from: https://www.jhrsonline.org/article.asp?issn=0974-1208;year=2014;volume=7;issue=3;spage=194;epage=197;aulast=Kaur;type=0