Journal of Human Reproductive Science
Home Ahead of Print Current Issue Archives
   Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size    Users online: 918


 
ORIGINAL ARTICLE Table of Contents   
Year : 2021  |  Volume : 14  |  Issue : 1  |  Page : 11-15
Inflammatory markers in peripheral blood cells cannot predict intrauterine insemination outcome: A retrospective cohort study


Department of Obstetrics and Gynecology, Zekai Tahir Burak Women's Health Care Training and Research Hospital, University of Health Sciences, Ankara, Turkey

Correspondence Address:
A Seval Ozgu-Erdinc
Zekai Tahir Burak Womenfs Health Education and Research Hospital, University of Health Sciences, Talatpasa Bulvari, Hamamonu, Altindag, Ankara 06230
Turkey
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jhrs.jhrs_216_20

Rights and Permissions

Background: Although infertility is known as a chronic inflammatory condition, the effect of the increased inflammatory response on IUI success is not clear. Systemic inflammation can be calculated by applying various hematological markers. Aims: We aimed to evaluate the ability of hematologic parameters of inflammation in predicting intrauterine insemination (IUI) outcome. Study Setting and Design: A total of 334 infertile couples included in this retrospective cohort study. The study population comprised of all couples who were candidates for ovulation induction and IUI due to polycystic ovary syndrome (PCOS) (n = 147) or unexplained infertility (UI) (n = 187). Materials and Methods: The inflammatory parameters in the complete blood count parameters, such as neutrophil-lymphocyte ratio, platelet lymphocyte ratio, platelet distribution width, plateletcrit were obtained on IUI day and compared between the two groups. The predictive values of these markers for IUI outcome were calculated. Results: There were 44 pregnancies (13.2%) in the whole study cohort. There were no significant differences between the pregnant and nonpregnant groups regarding the evaluated parameters (all P > 0.05). Also, no significant difference was observed between the patients with PCOS and UI in terms of those parameters. The area under receiver operating characteristic (ROC) curve analysis revealed that none of the inflammatory markers can predict pregnancy in intrauterine insemination cycles. Further prospective studies are needed to verify our findings. Conclusion: We found no relationship between the hematologic inflammatory markers and IUI outcome.Therefore these markers cannot be used for prediction of pregnancy.


[FULL TEXT] [PDF]*
Print this article  Email this article
    

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed687    
    Printed2    
    Emailed0    
    PDF Downloaded75    
    Comments [Add]    

Recommend this journal