Journal of Human Reproductive Science
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CASE REPORT Table of Contents   
Year : 2020  |  Volume : 13  |  Issue : 3  |  Page : 242-244
Hemoptysis: A rare presentation of mixed gonadal dysgenesis


Department of Endocrinology, Trivandrum Medical College, Thiruvananthapuram, Kerala, India

Correspondence Address:
Darvin V Das
Assistant Professor, Department of Endocrinology, Government Medical College, Thiruvananthapuram-695 541, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jhrs.JHRS_51_20

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The objective of the study was to present a case report on a phenotypic male mixed gonadal dysgenesis (MGD) who presented with hemoptysis due to secondary lung metastasis from dysgerminoma. Phenotypic male MGD (45, X/46, XY) with primary infertility and hemoptysis participated in the study. This study was conducted at a tertiary care center. Laparoscopic visualization of gonads and presence of Müllerian/ Wolffian structures were ascertained. Gonadectomy of intra abdominal dysgenetic gonad were done. Fluorescence in situ hybridization analysis was done in gonadal tissue to find the presence of Y chromosome. Intra-abdominal gonad showed dysgerminoma changes. Müllerian structures in the form of rudimentary uterus and fallopian tubes were seen. Left inguinal gonad showed normal testicular structures. Chemotherapy for secondary lung metastasis contemplated.


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