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 Indian J Med Microbiol  
 

Figure 1: The spectrum of Mycobacterium tuberculosis infection outcome. Bacterial burden (dashed orange line) is expected to increase the spectrum of infection. (p) pro- and (a) anti-inflammatory factors in the granuloma. Too much pro-inflammatory or too much anti-inflammatory activity can lead to poor control of bacteria and increased pathology. The purple line reflects the risk of reactivation in the latent spectrum. (Reprinted with permission from Lin PL, Flynn JL. Understanding latent tuberculosis: a moving target. J Immunol 2010;185 (1):15-22.)

Figure 1: The spectrum of <i>Mycobacterium tuberculosis</i> infection outcome. Bacterial burden (dashed orange line) is expected to increase the spectrum of infection. (p) pro- and (a) anti-inflammatory factors in the granuloma. Too much pro-inflammatory or too much anti-inflammatory activity can lead to poor control of bacteria and increased pathology. The purple line reflects the risk of reactivation in the latent spectrum. (Reprinted with permission from Lin PL, Flynn JL. Understanding latent tuberculosis: a moving target. J Immunol 2010;185 (1):15-22.)