Journal of Human Reproductive Sciences

CASE REPORT
Year
: 2013  |  Volume : 6  |  Issue : 1  |  Page : 79--81

Oral contraceptive pills: A risk factor for retinal vascular occlusion in in-vitro fertilization patients


Rohina S Aggarwal1, Vineet V Mishra1, Somesh V Aggarwal2 
1 Department of Obstetrics and Gynecology, Institute of Kidney Diseases and Transplantation Sciences, Ahmedabad, Gujarat, India
2 Manekchand and Jagjivan Ram Western Regional Institute of Ophthalmology, Retina Unit, Ahmedabad, Gujarat, India

Correspondence Address:
Rohina S Aggarwal
B 102, Anand Milan Tower, Near Municipal Garden, Shahibaug, Ahmedabad, Gujarat
India

Retinal vascular occlusion is the most common cause of retinopathy leading to severe visual loss in all age groups. Central retinal vein occlusion (CRVO) is usually seen in older age group and is often associated with systemic vascular diseases. Although the exact cause and effect relationship has not been proven, central retinal vein occlusion has been associated with various systemic pathological conditions, hence a direct review of systems toward the various systemic and local factors predisposing the central retinal vein occlusion is advocated. We describe the development of central retinal venous occlusion with associated cystoid macular edema (CME) in two healthy infertile women who were recruited for in vitro fertilization cycle for infertility. Predisposing risk factors associated with central retinal vein occlusion are obesity, sedentary life style, smoking, and some systemic diseases such as hyperlipidemia, hypertension, associated autoimmune disorders e.g., antiphospholipid antibody syndrome, lupus, diabetes mellitus, cardiovascular disorders, bleeding or clotting disorders, vasculitis, closed-head trauma, alcohol consumption, primary open-angle glaucoma or angle-closure glaucoma.In our patients, they were ruled out afterdoing allpertaining investigations. The cases were managed with further avoidance of oral contraceptives and intra-vitreal injections of Bevacizumab (Avastin), an anti-vascular endothelial growth factor (anti-VEGF drug) and Triamcinolone acetonide (a long acting synthetic steroid). Hence, even if no systemic diseases are detected. Physical examinations are recommended periodically for young women on oral contraceptive pills.


How to cite this article:
Aggarwal RS, Mishra VV, Aggarwal SV. Oral contraceptive pills: A risk factor for retinal vascular occlusion in in-vitro fertilization patients.J Hum Reprod Sci 2013;6:79-81


How to cite this URL:
Aggarwal RS, Mishra VV, Aggarwal SV. Oral contraceptive pills: A risk factor for retinal vascular occlusion in in-vitro fertilization patients. J Hum Reprod Sci [serial online] 2013 [cited 2020 Aug 4 ];6:79-81
Available from: http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2013;volume=6;issue=1;spage=79;epage=81;aulast=Aggarwal;type=0