Journal of Human Reproductive Science
Home Ahead of Print Current Issue Archives
   Bookmark this page Print this page Email this page Small font sizeDefault font size Increase font size    Users online: 440


 
CASE REPORT Table of Contents   
Year : 2020  |  Volume : 13  |  Issue : 1  |  Page : 68-70
Complex chromosomal rearrangement: A case report to emphasize the need for parental karyotyping and genetic counseling


Department of Genetics, Thyrocare Technologies Limited, Navi Mumbai, Maharashtra, India

Correspondence Address:
Ms. Sneha Ramesh Devi
Department of Genetics, Thyrocare Technologies Limited, Plot No. D37/1, TTC Industrial Area, MIDC, Turbhe, Navi Mumbai - 400 703, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jhrs.JHRS_145_19

Rights and Permissions

Complex chromosomal rearrangements (CCRs) are rare structural rearrangements which involve at least three or more chromosomal breaks. The present report emphasizes the significance of parental karyotyping and the need of genetic counseling for couples with bad obstetric history (repeated abortions/miscarriages). The report includes the cytogenetic assessment of the proband and the mother, carried out at our accredited laboratory. The karyotype analysis of the proband revealed an apparently balanced translocation, identified to have been familially inherited from the mother having CCRs with double two-way translocations involving four chromosomes.


[FULL TEXT] [PDF]*
Print this article  Email this article
    

  Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   Citation Manager
  Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed111    
    Printed0    
    Emailed0    
    PDF Downloaded10    
    Comments [Add]    

Recommend this journal