Journal of Human Reproductive Science
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CASE REPORT Table of Contents   
Year : 2018  |  Volume : 11  |  Issue : 1  |  Page : 75-78
Live birth after rescue in vitro maturation–intracytoplasmic sperm injection in type 1 diabetes, polycystic ovary syndrome patient using clomiphene–antagonist protocol


Department of IVF and Genetics, Srushti Fertility Centre and Women's Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
M Elanchezhian
#2, Dhandayuthapani Nagar, 2nd Street, Kotturpuram, Chennai - 600 085, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jhrs.JHRS_65_17

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Infertility in patients with polycystic ovary syndrome (PCOS) associated with diabetes leads to challenging situations seeking alternative treatments. In vitro maturation (IVM) followed by intracytoplasmic sperm injection (ICSI) could overcome the challenges with promising pregnancies in such patients. In the treatment of a 32-year-old diabetic woman who also had PCOS, single immature oocyte was retrieved. Rescue IVM followed by ICSI yielded a grade 1 day 3 embryo which on transferring resulted in pregnancy and a healthy infant was delivered. Rescue IVM–ICSI could help in achieving pregnancy and live birth. Stimulation involving clomiphene and gonadotropin-releasing hormone antagonist is an effective and patient-friendly protocol for women with PCOS and diabetes and also for poor responders.


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