Journal of Human Reproductive Science
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ORIGINAL ARTICLE Table of Contents   
Year : 2014  |  Volume : 7  |  Issue : 2  |  Page : 143-147
Effect of endometriosis on implantation rates when compared to tubal factor in fresh non donor in vitro fertilization cycles


Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Neeta Singh
Department of Obstetrics and Gynecology, Room No. 3090A, Third Floor, All India Institute of Medical Sciences, Ansari Nagar, New Delhi - 110 029
India
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Source of Support: All India Institute of Medical Sciences, Conflict of Interest: None


DOI: 10.4103/0974-1208.138874

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Objective : The objective of the following study is to compare the outcome of in vitro fertilization and embryo transfer (IVF-ET) in women with endometriosis and tubal-factor infertility. Design : Retrospective study. Setting : Tertiary referral hospital, assisted reproductive technologies unit. Materials and Method : The study group consisted of 78 women diagnosed with advanced stage endometriosis. The control group included 100 women with tubal-factor infertility. These groups were retrospectively analyzed regarding stimulation, fertilization, embryo development, implantation and pregnancy outcome. Intervention (S) : Controlled ovarian hyperstimulation and IVF-ET. Results : Lower oocyte yield with lower fertilization rate were found in women with endometriosis compared with tubal-factor control subjects. However, no differences were found in cleavage, implantation and clinical pregnancy rates between the endometriosis and tubal-factor groups. Conclusions : Our results showed that women with endometriosis have a lower oocyte yield and lower fertilization rate compared with women with tubal-factor infertility. However, once the oocyte is fertilized, it seems that the embryo has a normal chance of implantation, leading to similar pregnancy rates and adequately treated women with endometriosis have equal chances of conception as seen with tubal-factor infertility.


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